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- DOI 10.18231/j.jooo.79495.1759120703
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- Citation
Medication induced osteonecrosis of jaw: A detailed review
- Author Details:
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Niketan Deokisan Durge *
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Deepa Das
Medication-related osteonecrosis of the jaw (MRONJ) is a rare but serious condition associated with antiresorptive and antiangiogenic drugs, commonly used in treating osteoporosis and various cancers. The pathogenesis is multifactorial, involving impaired bone remodelling, infection, reduced angiogenesis, and immune suppression. MRONJ is more prevalent among cancer patients than those treated for osteoporosis. Clinically, it presents with exposed necrotic bone, pain, swelling, and secondary infections, significantly affecting the quality of human life. Diagnosis is clinical, supported by imaging and patient history. Management includes conservative or surgical approaches, with prevention being the most effective strategy. A multidisciplinary approach involving dentists, oncologists, and oral surgeons is essential for early diagnosis and treatment planning to minimize complications and improve patient outcomes. The purpose of this review is to shed light on the road map for clinical and radiographic diagnosis, prevention, and management of medication-related osteonecrosis of the jaw (MRONJ).
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How to Cite This Article
Vancouver
Durge ND, Das D. Medication induced osteonecrosis of jaw: A detailed review [Internet]. J Oral Med Oral Surg Oral Pathol Oral Radiol. 2025 [cited 2025 Oct 02];11(3):98-104. Available from: https://doi.org/10.18231/j.jooo.79495.1759120703
APA
Durge, N. D., Das, D. (2025). Medication induced osteonecrosis of jaw: A detailed review. J Oral Med Oral Surg Oral Pathol Oral Radiol, 11(3), 98-104. https://doi.org/10.18231/j.jooo.79495.1759120703
MLA
Durge, Niketan Deokisan, Das, Deepa. "Medication induced osteonecrosis of jaw: A detailed review." J Oral Med Oral Surg Oral Pathol Oral Radiol, vol. 11, no. 3, 2025, pp. 98-104. https://doi.org/10.18231/j.jooo.79495.1759120703
Chicago
Durge, N. D., Das, D.. "Medication induced osteonecrosis of jaw: A detailed review." J Oral Med Oral Surg Oral Pathol Oral Radiol 11, no. 3 (2025): 98-104. https://doi.org/10.18231/j.jooo.79495.1759120703