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- DOI 10.18231/j.jooo.11528.1754639285
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CrossMark
Basal cell ameloblastoma in the mandibular symphysis: A unique case report of a rare histological variant with uncommon presentation
- Author Details:
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Shadiya C *
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Anshul Aggarwal
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Md. Asdullah
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Pradhuman Verma
Shadiya C *
Anshul Aggarwal
Md. Asdullah
Pradhuman Verma
Basal cell ameloblastoma is an uncommon histological variant of ameloblastoma, characterised by basaloid epithelial cells with minimal peripheral palisading, often mimicking other basaloid neoplasms. We report a case of a 64-year-old male presenting with a five-year history of swelling in the anterior mandible. Radiographic assessment including orthopantomography and computed tomography revealed a well-demarcated intraosseous lesion in the symphyseal region. A definitive diagnosis was established through histopathological examination, confirming basal cell ameloblastoma. Due to its rarity and histopathological overlap with malignancies such as basal cell carcinoma and adenoid cystic carcinoma, accurate diagnosis necessitates comprehensive clinicopathological correlation. Given the limited data on its biological behaviour, long-term follow-up is advised.
References
- Kramer IR, Pindborg JJ, Shear M. Histological Typing of Odontogenic Tumors. 2nd ed. Berlin: Springer-Verlag; 1992. p. 11,
- Adebiyi KE, Ugboko VI, Omoniyi-Esan GO, Ndukwe KC, Oginni FO. Clinicopathological analysis of histological variants of ameloblastoma in a suburban Nigerian population. Head Face Med. 2006;2:42. https://doi.org/10.1186/1746-160X-2-42
[Google Scholar] - Kashyap N, Rakshit S, Aravindan S, Srihari S. Basal cell ameloblastoma: A rare variant with a comprehensive literature review. Med Rep. 2025;13:100258. https://doi.org/10.1016/j.hmedic.2025.100258
[Google Scholar] - Shakya H, Khare V, Pardhe N, Mathur E, Chouhan M. Basal cell ameloblastoma of mandible: a rare case report with review. Case Rep Dent. 2013;2013:187820. https://doi.org/10.1155/2013/187820
[Google Scholar] - Saify F, Sharma N. Basal cell ameloblastoma: A rare case report and review of literature. Oral Maxillofac Pathol J. 2010;1:1–7. Shadiya C et al. /Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology 2025;11(3):129–133 133
- Sridhar M, Reddy LRB, Kharat S, Mahesh BS, Gandi L, Mahendra A, et al. Basal cell ameloblastoma: a rare histological variant of an uncommon tumor. Niger J Surg. 2015;21(1):66–9. https://doi.org/10.4103/1117-6806.152730
[Google Scholar] - Kaur M, Bhat N. Aggressive basal cell ameloblastoma: A rare diagnostic enigma. Int J Curr Adv Res. 2020;9:21529–31.
- Del Rosario RN, Barr RJ, Jensen JL, Cantos KA. Basal cell carcinoma of the buccal mucosa. Am J Dermatopathol. 2001;23(3):203–5. https://doi.org/10.1097/00000372-200106000-
[Google Scholar] - Emanuel P, Wang B, Wu M, Burstein DE. p63 immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma. Mod Pathol. 2005;18(5):645–50. https://doi.org/10.1038/modpathol.3800329
[Google Scholar] - Sandra F, Mitsuyasu T, Nakamura N, Shiratsuchi Y, Ohishi M. Immunohistochemical evaluation of PCNA and Ki-67 in ameloblastoma. Oral Oncol. 2001;37(2):193–8. https://doi.org/10.1016/s1368-8375(00)00079-8
[Google Scholar] - Ueda M, Kaneda T. Combined chemotherapy and radiotherapy for advanced maxillary ameloblastoma. A case report. J Craniomaxillofac Surg. 1991;19(6):272–4. https://doi.org/10.1016/s1010-5182(05)80069-1
[Google Scholar] - Vohra FA, Hussain M, Mudassir MS. Ameloblastomas and their management: a review. J Surg Pak Int. 2009;14:136–42.
- Antonoglou GN, Sándor GK. Recurrence rates of intraosseous ameloblastomas of the jaws: a systematic review of conservative versus aggressive treatment approaches and meta-analysis of non- randomized studies. J Craniomaxillofac Surg. 2015;43(1):149–57. https://doi.org/10.1016/j.jcms.2014.10.027
[Google Scholar]