Assessment of effect of Epinephrine in diabetic patients undergoing third molar extraction

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Original Article

Author Details : Hemanth Kumar HR, Vinuta Hegde, Rakesh Sharma

Volume : 3, Issue : 3, Year : 2017

Article Page : 149-152

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Abstract

Introduction: The most common endocrine disorders reported worldwide is diabetes and various literature have shown alteration in the plasma glucose levels after use of dental local anaesthetic containing adrenaline which has been a subject of controversy. The study was undertaken to evaluate the effect of epinephrine in healthy and diabetic patient undergoing third molar extraction.
Materials and Method: The present study was done in Department of Dentistry, Karwar Institute of Medical Sciences, Karwar. A total of 150 patients reporting to the hospital for the purpose of third molar extraction were included in the study. Electronic glucometer was used to estimate the blood glucose level in study group before administrating Local Anaesthesia (LA), after administrating LA and after third molar extraction. Postoperative suturing was done in all patients. The data was tabulated and analysed using SPSS software. The results were compared using student t test.
Result: The mean age of the patients was 36.2 ± 8.9 years. Before and after administration of LA the mean glucose levels in Group I were 107.5±20.2 mg/dl and 108.7±19.2 mg/dl, in Group II it was195.3±29.1 mg/dl and 197.5±30.5 mg/dl and in Group III it was 170.5±23.1mg/dl and 168.5±22.7 mg/dl respectively showing no significant difference in glucose level before and after administration of LA.Before and after extraction the mean glucose level in Group I were 107.5±20.2 mg/dl and 105.5±21.3 mg/dl, in Group II 195.3±29.1 mg/dl and 199.9±32.2 mg/dl and in Group III it was 170.5±23.1 mg/dl and 223.7±43.4 mg/dl respectively showing a significant difference in glucose level in Group III patients before and after tooth extraction with p value lesser than 0.05.
Conclusion: It was observed that adrenaline does not exert any significant affect on healthy and diabetic patients but in patients with untreated diabetes the glucose levels tend to rise significantly if local anaesthesia with adrenaline is administered.

Keywords: Adrenaline, Diabetes, Extraction, Glucose, Third molar

How to cite : Hemanth Kumar Hr, Hegde V, Sharma R, Assessment of effect of Epinephrine in diabetic patients undergoing third molar extraction. J Oral Med Oral Surg Oral Pathol Oral Radiol 2017;3(3):149-152

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